What are the major differences between mfiles web and desktop versions??

This may help:

M-Files Feature Comparison.pdf (Desktop, Web, Mobile)

Thank you

A more detailed comparison between M-Files Desktop and the classic M-Files Web also available, this provides some background information about why some features are missing in web clients (mostly due to the technical restrictions of a browser environment): M-Files Desktop vs. Classic M-Files Web

Thanks a ton !!