Automatic Multifile generation

Yes, this is possible. The exact approach depends on the detailed use case.

For instance, if you want to have a project template that has placeholder multi-file documents and that you use to create the structure for new projects, you can use Object Creator module for that. You would set up the template project manually (create the empty MFDs and relate them to the template project and so on) and then configure Object Creator to enable users to create a copy of this template when starting a new project.

Other scenarios may require some development effort, for instance if you would like to create these multi-file documents when an object enters a specific workflow state.